Radiotherapy: technical aspects

Radiotherapy for laryngeal cancer—technical aspects and alternate fractionation

Early laryngeal, especially glottic, cancer is a good candidate for radiotherapy because obvious early symptoms (e.g. hoarseness) make earlier treatment possible and with highly successful localized control. This type of cancer is also a good model for exploring the basic principles of radiation oncology and several key findings (e.g. dose, fractionation, field size, patient fixation, and overa...

Immunological aspects of radiotherapy

The major objective of radiotherapy (RT) in the context of cancer treatment is the achievement of local tumor control. Traditionally, this is considered to be mediated by the induction of DNA damage, resulting in tumor cell death and abrogated clonogenic survival [1]. However, it has become more and more evident that distinct irradiation regimes as well as selected doses of ionizing radiation, ...

Tumour ablation: technical aspects

Image-guided percutaneous radiofrequency ablation (RFA) is a minimally invasive, relatively low-risk procedure for tumour treatment. Local recurrence and survival rates depend on the rate of complete ablation of the entire tumour including a sufficient margin of surrounding healthy tissue. Currently a variety of different RFA devices are available. The interventionalist must be able to predict ...

Technical aspects of the data

Total mesorectal excision: technical aspects.

Total mesorectal excision (TME) is a precise dissection of the rectum and all pararectal lymph nodes within an oncologic package: the mesorectal envelope. This article is a brief description of the technical aspects of the dissection, illustrated by cadaver dissection. Here the TME dissection is organized into 6 steps to facilitate learning: (1) left retroperitoneum; (2) superior rectal and inf...